Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WecEPredicted pyridoxal phosphate-dependent enzyme; Involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. (364 aa)    
Predicted Functional Partners:
PTH_1075
Predicted nucleoside-diphosphate sugar epimerases.
 
  
 0.871
WcaJ-2
Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.816
RfbX
Membrane protein; Involved in the export of O-antigen and teichoic acid.
  
  
 0.794
PTH_0380
Carbonic anhydrases/acetyltransferases; Isoleucine patch superfamily.
  
 0.644
MviM
Predicted dehydrogenases and related proteins.
 
  
 0.631
WecC
UDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.510
PTH_0395
Hypothetical membrane protein.
       0.489
PTH_1120
Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases.
  
  
 0.480
RfbA
dTDP-glucose pyrophosphorylase.
  
  
 0.459
RfbA-2
dTDP-glucose pyrophosphorylase.
  
  
 0.459
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (24%) [HD]