Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AmiC-2N-acetylmuramoyl-L-alanine amidase. (233 aa)    
Predicted Functional Partners:
GlpG
Uncharacterized membrane protein; Homolog of Drosophila rhomboid.
   
   0.797
MurI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.636
MurI-2
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.636
PTH_0436
Hypothetical membrane protein.
       0.576
PTH_0437
Uncharacterized conserved protein; Related to C-terminal domain of eukaryotic chaperone, SACSIN.
       0.576
ArsR-2
Predicted transcriptional regulator.
       0.550
PTH_0168
Hypothetical membrane protein.
 
      0.537
PTH_0440
Predicted methyltransferase.
       0.445
PTH_0792
Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
     0.420
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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