| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AmiC-2 | ArsR-2 | PTH_0438 | PTH_0439 | N-acetylmuramoyl-L-alanine amidase. | Predicted transcriptional regulator. | 0.550 |
| AmiC-2 | GlpG | PTH_0438 | PTH_2662 | N-acetylmuramoyl-L-alanine amidase. | Uncharacterized membrane protein; Homolog of Drosophila rhomboid. | 0.797 |
| AmiC-2 | MurI | PTH_0438 | PTH_0787 | N-acetylmuramoyl-L-alanine amidase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.636 |
| AmiC-2 | MurI-2 | PTH_0438 | PTH_0922 | N-acetylmuramoyl-L-alanine amidase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.636 |
| AmiC-2 | PTH_0168 | PTH_0438 | PTH_0168 | N-acetylmuramoyl-L-alanine amidase. | Hypothetical membrane protein. | 0.537 |
| AmiC-2 | PTH_0436 | PTH_0438 | PTH_0436 | N-acetylmuramoyl-L-alanine amidase. | Hypothetical membrane protein. | 0.576 |
| AmiC-2 | PTH_0437 | PTH_0438 | PTH_0437 | N-acetylmuramoyl-L-alanine amidase. | Uncharacterized conserved protein; Related to C-terminal domain of eukaryotic chaperone, SACSIN. | 0.576 |
| AmiC-2 | PTH_0440 | PTH_0438 | PTH_0440 | N-acetylmuramoyl-L-alanine amidase. | Predicted methyltransferase. | 0.445 |
| AmiC-2 | PTH_0792 | PTH_0438 | PTH_0792 | N-acetylmuramoyl-L-alanine amidase. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.420 |
| ArsR-2 | AmiC-2 | PTH_0439 | PTH_0438 | Predicted transcriptional regulator. | N-acetylmuramoyl-L-alanine amidase. | 0.550 |
| ArsR-2 | PTH_0436 | PTH_0439 | PTH_0436 | Predicted transcriptional regulator. | Hypothetical membrane protein. | 0.421 |
| ArsR-2 | PTH_0437 | PTH_0439 | PTH_0437 | Predicted transcriptional regulator. | Uncharacterized conserved protein; Related to C-terminal domain of eukaryotic chaperone, SACSIN. | 0.421 |
| ArsR-2 | PTH_0440 | PTH_0439 | PTH_0440 | Predicted transcriptional regulator. | Predicted methyltransferase. | 0.771 |
| GlpG | AmiC-2 | PTH_2662 | PTH_0438 | Uncharacterized membrane protein; Homolog of Drosophila rhomboid. | N-acetylmuramoyl-L-alanine amidase. | 0.797 |
| MurI | AmiC-2 | PTH_0787 | PTH_0438 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | N-acetylmuramoyl-L-alanine amidase. | 0.636 |
| MurI | MurI-2 | PTH_0787 | PTH_0922 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.912 |
| MurI | PTH_0792 | PTH_0787 | PTH_0792 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.926 |
| MurI-2 | AmiC-2 | PTH_0922 | PTH_0438 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | N-acetylmuramoyl-L-alanine amidase. | 0.636 |
| MurI-2 | MurI | PTH_0922 | PTH_0787 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.912 |
| MurI-2 | PTH_0792 | PTH_0922 | PTH_0792 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.433 |