Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_0445Hypothetical membrane protein; Containing NapF, ferredoxin (COG1145). (300 aa)    
Predicted Functional Partners:
GltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 0.942
PTH_2234
Uncharacterized conserved protein; Containing a ferredoxin-like domain.
  
 
 0.917
RnfC
Predicted NADH:ubiquinone oxidoreductase, subunit RnfC.
  
 
 0.845
HdrB
Heterodisulfide reductase, subunit B.
 
 
 0.830
HdrA-2
Heterodisulfide reductase, subunit A and related polyferredoxins.
 
 
 0.778
PTH_1377
Hypothetical hydrogenase subunit; Containing COG3383, Uncharacterized anaerobic dehydrogenase, COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).
   
 
 0.761
PTH_2010
NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit, chain G.
   
 
 0.761
HyaB
Ni,Fe-hydrogenase I large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
 
 0.742
HdrA
Heterodisulfide reductase, subunit A and related polyferredoxins.
 
 
 0.733
PTH_1005
Hypothetical protein.
 
   
 0.629
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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