STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DegQTrypsin-like serine proteases; Typically periplasmic, contain C-terminal PDZ domain. (386 aa)    
Predicted Functional Partners:
BaeS
Signal transduction histidine kinase.
  
 0.689
PTH_1597
Hypothetical protein; Containing COG3852 NtrB, signal transduction histidine kinase and COG3706 PleD, response regulator containing a CheY-like receiver domain and a GGDEF domain.
  
  
 0.669
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
  
 0.645
OmpR-4
Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.594
RpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
 
 
 0.549
PTH_1118
Hypothetical protein; Containing WcaA (COG0463), glycosyltransferases involved in cell wall biogenesis and PilF (COG3063), tfp pilus assembly protein PilF.
  
 0.533
RplY
Ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
 
   0.472
RplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
    
   0.451
GltB-2
Glutamate synthase domain 2.
     
 0.450
DnaK
Molecular chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.425
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.