Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
OmpR-4Response regulator; Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (225 aa)    
Predicted Functional Partners:
BaeS
Signal transduction histidine kinase.
 
 0.966
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.949
VicK
Signal transduction histidine kinase.
 
 0.937
PTH_1727
Hypothetical signaling protein; Containing FOG:GGDEF domain (COG2199) and ResE, FOG: HAMP domain (COG2770).
 
 0.935
PTH_0246
Hypothetical protein; Containing BaeS signal transduction histidine kinase (COG0642).
 
 0.912
PTH_0036
Hypothetical membrane-associated sensory histidine kinase; Containing COG5002, VicK, signal transduction histidine kinase domain.
 
 0.905
BaeS-2
Signal transduction histidine kinase.
 
 0.891
BaeS-4
Signal transduction histidine kinase.
 
 
0.887
PTH_2130
Hypothetical protein.
 
      0.880
PTH_0047
Hypothetical signal transduction protein; Containing partial KdpD (COG2205).
 
 0.875
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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