Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTH_0467Hypothetical protein; Containing AMMECR1 uncharacterized conserved protein (COG2078) and uncharacterized conserved protein (COG3885). (466 aa)    
Predicted Functional Partners:
PflA
Pyruvate-formate lyase-activating enzyme.
     0.954
RhtB
Putative threonine efflux protein.
       0.605
PTH_0464
Hypothetical membrane protein.
       0.570
nnrE
Predicted Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...]
  
  
 0.507
PTH_0469
Hypothetical protein; Containing DRG, predicted GTPase (COG1163) and TGS domain.
       0.469
PTH_0994
Predicted Fe-S oxidoreductases.
  
     0.467
PTH_0465
Hypothetical protein.
       0.456
PTH_0463
Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB.
       0.423
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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