STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PflAPyruvate-formate lyase-activating enzyme. (336 aa)    
Predicted Functional Partners:
PTH_0467
Hypothetical protein; Containing AMMECR1 uncharacterized conserved protein (COG2078) and uncharacterized conserved protein (COG3885).
     0.957
PflD
Pyruvate-formate lyase.
  
  
 0.666
PTH_1584
Putative aldehyde/alcohol dehydrogenase; Containing PutA (COG1012), NAD-dependent aldehyde dehydrogenases and EutG (COG1454) alcohol dehydrogenase class IV; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.597
RhtB
Putative threonine efflux protein.
       0.526
PTH_0469
Hypothetical protein; Containing DRG, predicted GTPase (COG1163) and TGS domain.
       0.519
PTH_0464
Hypothetical membrane protein.
       0.513
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.457
PflX
Uncharacterized Fe-S protein; Homolog of pyruvate formate lyase activating proteins.
  
     0.430
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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