Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NfnBNitroreductase. (188 aa)    
Predicted Functional Partners:
GltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
      
 0.624
GltD-2
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
      
 0.624
GltD-3
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
      
 0.624
BirA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.578
Tig
FKBP-type peptidyl-prolyl cis-trans isomerase; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
      
 0.521
HybF
Zn finger protein HypA/HybF; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
      
 0.510
PTH_2277
Hypothetical protein.
  
  
 0.509
PTH_2329
Uncharacterized conserved protein.
  
  
 0.509
RpmI
Ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family.
     
 0.498
MmcG
methylmalonyl-CoA epimerase; Lactoylglutathione lyase and related lyases.
  
  
 0.496
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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