STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
PTH_04812-keto-4-pentenoate hydratase. (261 aa)    
Predicted Functional Partners:
LeuA
Isopropylmalate/homocitrate/citramalate synthases; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.993
MhpF
Acetaldehydede hydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.988
NadC-2
Nicotinate-nucleotide pyrophosphorylase.
 
     0.763
PTH_0485
Hypothetical protein; Containing MoCF_biosynth, Probable molybdopterin binding domain.
 
     0.725
PTH_0478
Hypothetical protein; Containing ferredoxin (COG1146).
 
     0.679
PTH_0479
Hypothetical protein.
       0.636
IclR-2
Transcriptional regulator.
 
  
 0.506
PheA
Prephenate dehydratase.
      
 0.440
EutG
Alcohol dehydrogenase; Class IV.
       0.406
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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