STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_0485Hypothetical protein; Containing MoCF_biosynth, Probable molybdopterin binding domain. (292 aa)    
Predicted Functional Partners:
NadC-2
Nicotinate-nucleotide pyrophosphorylase.
   
 0.960
PTH_0478
Hypothetical protein; Containing ferredoxin (COG1146).
 
     0.824
PTH_0489
Hypothetical membrane protein.
 
     0.733
PTH_0481
2-keto-4-pentenoate hydratase.
 
     0.727
HycB
Fe-S-cluster; Containing hydrogenase components 2.
 
     0.727
PTH_0487
Aldehyde:ferredoxin oxidoreductase.
 
     0.699
EutG
Alcohol dehydrogenase; Class IV.
 
     0.667
MhpF
Acetaldehydede hydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
     0.653
PTH_2456
Hypothetical protein.
  
     0.596
LeuA
Isopropylmalate/homocitrate/citramalate synthases; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
     0.558
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.