Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FabGDehydrogenases with different specificities; Related to short-chain alcohol dehydrogenases. (267 aa)    
Predicted Functional Partners:
NemA-2
NADH:flavin oxidoreductases; Containing TrxB (COG0492), thioredoxin reductase domain.
 
 
 0.750
SbcD
DNA repair exonuclease.
   
 
 0.734
PTH_0594
Predicted Fe-S oxidoreductases.
 
  
 0.705
FabD
(acyl-carrier-protein) S-malonyltransferase.
 
 0.704
NemA
NADH:flavin oxidoreductases; Old Yellow Enzyme family.
 
  
 0.686
PTH_0590
Hypothetical protein.
       0.675
PTH_0591
Hypothetical protein.
       0.675
AdhP
Zn-dependent alcohol dehydrogenases.
  
  
 0.647
guaB
Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.638
PaaJ
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.632
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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