Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MoaDMolybdopterin converting factor, small subunit. (99 aa)    
Predicted Functional Partners:
ThiF-3
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
  
 0.973
ThiF
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
  
 0.926
ThiF-2
Dinucleotide-utilizing enzymes; Involved in molybdopterin and thiamine biosynthesis family 2.
  
 0.926
ThiS
Sulfur transfer protein; Involved in thiamine biosynthesis.
     
  0.900
MoaC
Molybdenum cofactor biosynthesis enzyme; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.667
PTH_0610
Aldehyde:ferredoxin oxidoreductase.
       0.532
MoaA
Molybdenum cofactor biosynthesis enzyme; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
  
 0.509
MoaB
Molybdopterin biosynthesis enzyme; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
  
  
 0.469
HycB-2
Fe-S-cluster-containing hydrogenase components 2.
     
 0.461
PTH_0613
Secreted protein; Containing C-terminal beta-propeller domain distantly related to WD-40 repeats.
       0.414
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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