| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CitB | FliA-4 | PTH_1203 | PTH_1845 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.838 |
| CitB | PTH_0124 | PTH_1203 | PTH_0124 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein. | 0.761 |
| CitB | PTH_0185 | PTH_1203 | PTH_0185 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical membrane protein. | 0.834 |
| CitB | PTH_0638 | PTH_1203 | PTH_0638 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein; Containing AbrB regulators of stationary/sporulation gene expression (COG2002) domain. | 0.797 |
| CitB | PTH_1229 | PTH_1203 | PTH_1229 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein]. | 0.820 |
| CitB | PTH_1605 | PTH_1203 | PTH_1605 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.864 |
| CitB | PTH_2800 | PTH_1203 | PTH_2800 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Hypothetical protein. | 0.862 |
| CitB | RsbW | PTH_1203 | PTH_1225 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.831 |
| CitB | SpoIIIAA | PTH_1203 | PTH_1166 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Uncharacterized protein conserved in bacteria. | 0.785 |
| CitB | gpr | PTH_1203 | PTH_1755 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.764 |
| FliA-4 | CitB | PTH_1845 | PTH_1203 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.838 |
| FliA-4 | PTH_0124 | PTH_1845 | PTH_0124 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein. | 0.773 |
| FliA-4 | PTH_0185 | PTH_1845 | PTH_0185 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical membrane protein. | 0.797 |
| FliA-4 | PTH_0638 | PTH_1845 | PTH_0638 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein; Containing AbrB regulators of stationary/sporulation gene expression (COG2002) domain. | 0.790 |
| FliA-4 | PTH_1229 | PTH_1845 | PTH_1229 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein]. | 0.793 |
| FliA-4 | PTH_1605 | PTH_1845 | PTH_1605 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.793 |
| FliA-4 | PTH_2800 | PTH_1845 | PTH_2800 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein. | 0.791 |
| FliA-4 | RsbW | PTH_1845 | PTH_1225 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.920 |
| FliA-4 | SpoIIIAA | PTH_1845 | PTH_1166 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Uncharacterized protein conserved in bacteria. | 0.779 |
| FliA-4 | gpr | PTH_1845 | PTH_1755 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.782 |
