STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_0646Predicted phosphatase homologous; The C-terminal domain of histone macroH2A1. (232 aa)    
Predicted Functional Partners:
PTH_1052
ATPase; Related to the helicase subunit of the holliday junction resolvase.
      0.902
PTH_0645
Conserved protein; Domain typically associated with flavoprotein oxygenases, DIM6/NTAB family.
       0.773
Cmk
Cytidylate kinase.
 
      0.632
ArsR-4
Predicted transcriptional regulator.
  
    0.503
SIR2
NAD-dependent protein deacetylases; SIR2 family.
 
 
 0.441
PTH_0642
Predicted dinucleotide-utilizing enzyme; ThiF/HesA family.
  
    0.438
ThiE
Thiamine monophosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.425
ThiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
       0.425
ThiH-3
Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes.
       0.420
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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