Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HybAFe-S-cluster-containing hydrogenase components 1. (271 aa)    
Predicted Functional Partners:
BisC-2
Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 0.989
PTH_1711
Hypothetical formate dehydrogenase; Containing partial COG3383, Uncharacterized anaerobic dehydrogenase.
 
 0.987
FdnI
Cytochrome b subunit of formate dehydrogenase.
 
 0.976
NrfD-2
Polysulphide reductase; Transmembrane regions, NrfD perticipates in the transfer of electrons.
 
 0.933
NrfD
Polysulphide reductase; NrfD perticipates in the transfer of electrons from quinone pool into the therminal components.
 
 0.930
HycB
Fe-S-cluster; Containing hydrogenase components 2.
  
  
 
0.926
HycB-2
Fe-S-cluster-containing hydrogenase components 2.
  
  
 
0.923
PTH_0670
Hypothetical protein.
  
 
 0.920
HybA-2
Fe-S-cluster-containing hydrogenase components 1.
  
  
 
0.903
HybA-3
Fe-S-cluster-containing hydrogenase components 1.
  
  
 
0.903
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.