| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CobQ | CobS | PTH_0958 | PTH_1313 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.948 |
| CobQ | GpmB | PTH_0958 | PTH_0689 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Fructose-2,6-bisphosphatase. | 0.619 |
| CobQ | PTH_0956 | PTH_0958 | PTH_0956 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | precorrin-3B methylase and precorrin-6x reductase; COG1010, CobJ and COG2099, CobK. | 0.999 |
| CobS | CobQ | PTH_1313 | PTH_0958 | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.948 |
| CobS | GpmB | PTH_1313 | PTH_0689 | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | Fructose-2,6-bisphosphatase. | 0.846 |
| CobS | PTH_0956 | PTH_1313 | PTH_0956 | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | precorrin-3B methylase and precorrin-6x reductase; COG1010, CobJ and COG2099, CobK. | 0.999 |
| DeoB | GpmB | PTH_1211 | PTH_0689 | Hosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Fructose-2,6-bisphosphatase. | 0.741 |
| GpmB | CobQ | PTH_0689 | PTH_0958 | Fructose-2,6-bisphosphatase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.619 |
| GpmB | CobS | PTH_0689 | PTH_1313 | Fructose-2,6-bisphosphatase. | Cobalamin-5-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.846 |
| GpmB | DeoB | PTH_0689 | PTH_1211 | Fructose-2,6-bisphosphatase. | Hosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.741 |
| GpmB | PTH_0680 | PTH_0689 | PTH_0680 | Fructose-2,6-bisphosphatase. | Hypothetical protein; Containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.613 |
| GpmB | PTH_0682 | PTH_0689 | PTH_0682 | Fructose-2,6-bisphosphatase. | Hypothetical protein. | 0.628 |
| GpmB | PTH_0683 | PTH_0689 | PTH_0683 | Fructose-2,6-bisphosphatase. | Hypothetical membrane protein. | 0.675 |
| GpmB | PTH_0687 | PTH_0689 | PTH_0687 | Fructose-2,6-bisphosphatase. | Hypothetical protein. | 0.891 |
| GpmB | PTH_0688 | PTH_0689 | PTH_0688 | Fructose-2,6-bisphosphatase. | Hypothetical protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.615 |
| GpmB | PTH_0956 | PTH_0689 | PTH_0956 | Fructose-2,6-bisphosphatase. | precorrin-3B methylase and precorrin-6x reductase; COG1010, CobJ and COG2099, CobK. | 0.768 |
| GpmB | PaaK-3 | PTH_0689 | PTH_0685 | Fructose-2,6-bisphosphatase. | Coenzyme F390 synthetase. | 0.635 |
| PTH_0680 | GpmB | PTH_0680 | PTH_0689 | Hypothetical protein; Containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Fructose-2,6-bisphosphatase. | 0.613 |
| PTH_0680 | PTH_0682 | PTH_0680 | PTH_0682 | Hypothetical protein; Containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Hypothetical protein. | 0.918 |
| PTH_0680 | PTH_0683 | PTH_0680 | PTH_0683 | Hypothetical protein; Containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Hypothetical membrane protein. | 0.919 |