STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YSH1Predicted exonuclease of the beta-lactamase fold; Involved in RNA processing. (436 aa)    
Predicted Functional Partners:
rnj
Predicted hydrolase; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.
  
  
 
0.917
YSH1-2
Predicted exonuclease; The beta-lactamase fold involved in RNA processing.
  
  
 
0.916
PTH_0699
Hypothetical protein.
       0.773
PTH_0700
Hypothetical protein.
  
    0.648
rny
Hypothetical protein; Endoribonuclease that initiates mRNA decay.
  
 
 0.544
TopA
Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...]
 
  
 0.503
IspA
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.492
IspA-2
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.492
PTH_1440
Hypothetical protein; IspA (COG0142), geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
    0.492
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.