Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
GltBGlutamate synthase domain 2. (525 aa)    
Predicted Functional Partners:
GltB-2
Glutamate synthase domain 2.
  
 
 0.947
GltD-2
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.766
PTH_0680
Hypothetical protein; Containing GlpC (COG0247), Fe-S oxidoreductase and partial GltD (COG0493), NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.750
GltD
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.729
GltD-3
NADPH-dependent glutamate synthase beta chain and related oxidoreductases.
  
 
 0.729
PTH_1502
Hypothetical protein.
  
 
 0.729
GlnA-2
Glutamine synthetase.
  
  
 0.619
GdhA
Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.567
GlnA-3
Glutamine synthetase.
  
  
 0.552
guaA
Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.545
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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