node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CtsR | MazF | PTH_0280 | PTH_0738 | Transcriptional repressor of class III stress genes; Belongs to the CtsR family. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.571 |
FliD | MazF | PTH_2096 | PTH_0738 | Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.499 |
FtsZ | MazF | PTH_1850 | PTH_0738 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.584 |
FtsZ | PyrE | PTH_1850 | PTH_1804 | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.420 |
Hpt | MazF | PTH_2552 | PTH_0738 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.420 |
Hpt | PyrE | PTH_2552 | PTH_1804 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.444 |
HutI | MazF | PTH_0739 | PTH_0738 | Imidazolonepropionase and related amidohydrolases. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.581 |
HutI | PTH_0737 | PTH_0739 | PTH_0737 | Imidazolonepropionase and related amidohydrolases. | Hypothetical protein. | 0.606 |
HutI | PTH_0742 | PTH_0739 | PTH_0742 | Imidazolonepropionase and related amidohydrolases. | Inactive homolog of metal-dependent proteases; Putative molecular chaperone. | 0.494 |
IlvH-2 | MazF | PTH_0736 | PTH_0738 | Acetolactate synthase, small (regulatory) subunit. | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | 0.549 |
IlvH-2 | PTH_0737 | PTH_0736 | PTH_0737 | Acetolactate synthase, small (regulatory) subunit. | Hypothetical protein. | 0.553 |
MazF | CtsR | PTH_0738 | PTH_0280 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Transcriptional repressor of class III stress genes; Belongs to the CtsR family. | 0.571 |
MazF | FliD | PTH_0738 | PTH_2096 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Flagellar capping protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. | 0.499 |
MazF | FtsZ | PTH_0738 | PTH_1850 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.584 |
MazF | Hpt | PTH_0738 | PTH_2552 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.420 |
MazF | HutI | PTH_0738 | PTH_0739 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Imidazolonepropionase and related amidohydrolases. | 0.581 |
MazF | IlvH-2 | PTH_0738 | PTH_0736 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Acetolactate synthase, small (regulatory) subunit. | 0.549 |
MazF | PTH_0737 | PTH_0738 | PTH_0737 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Hypothetical protein. | 0.981 |
MazF | PTH_0742 | PTH_0738 | PTH_0742 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Inactive homolog of metal-dependent proteases; Putative molecular chaperone. | 0.419 |
MazF | PotE-2 | PTH_0738 | PTH_2207 | Growth inhibitor; Toxic component of a type II toxin-antitoxin (TA) system. | Amino acid transporters. | 0.452 |