Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RimIAcetyltransferases; Acetylates the N-terminal alanine of ribosomal protein S18. (96 aa)    
Predicted Functional Partners:
PTH_0742
Inactive homolog of metal-dependent proteases; Putative molecular chaperone.
 
 
 0.976
QRI7
Metal-dependent proteases; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 0.842
PTH_0741
Predicted ATPase or kinase.
  
  
 0.727
guaA
Hypothetical GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
   
 0.642
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.506
PTH_0744
Hypothetical protein; Containing FtsA resion (actin-like ATPase involved in cell division, COG0849).
       0.497
PTH_0745
Hypothetical protein.
       0.456
HutI
Imidazolonepropionase and related amidohydrolases.
       0.445
PTH_0746
Uncharacterized conserved protein.
       0.428
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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