Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PTH_0770Hypothetical membrane protein. (762 aa)    
Predicted Functional Partners:
PTH_0772
Hypothetical membrane protein.
 
    0.962
PTH_0769
Hypothetical membrane protein.
 
     0.947
CcmA-2
ABC-type multidrug transport system, ATPase component.
 
    0.946
RpoE-3
DNA-directed RNA polymerase specialized sigma subunit; Sigma24 homolog; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.836
PspA
Suppresse phage shock protein A; (IM30), sigma54-dependent transcription.
  
     0.689
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.593
RplF
Ribosomal protein L6P/L9E; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.584
HcaD
Uncharacterized NAD(FAD)-dependent dehydrogenases and rhodanese-related sulfurtransferase.
   
 
 0.558
PTH_1734
Uncharacterized NAD(FAD)-dependent dehydrogenases; Containing PspE, rhodanese-related sulfurtransferase (COG0607).
   
 
 0.558
RplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.557
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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