MurI protein (Pelotomaculum thermopropionicum)

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Score

MurI

Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (266 aa)

Predicted Functional Partners:

MurD

0.973

PTH_0792

0.929

MurI-2

0.912

PurL-2

0.900

AmiC-2

0.759

AmiC

0.754

AmiC-3

0.754

AmiC-4

0.754

AmiC-5

0.754

HgdB-2

0.635

Your Current Organism:

Pelotomaculum thermopropionicum

NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AmiC	MurI	PTH_0361	PTH_0787	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC	MurI-2	PTH_0361	PTH_0922	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-2	MurI	PTH_0438	PTH_0787	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.759
AmiC-2	MurI-2	PTH_0438	PTH_0922	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.759
AmiC-2	PTH_0792	PTH_0438	PTH_0792	N-acetylmuramoyl-L-alanine amidase.	Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.424
AmiC-3	MurI	PTH_1425	PTH_0787	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-3	MurI-2	PTH_1425	PTH_0922	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-4	MurI	PTH_1971	PTH_0787	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-4	MurI-2	PTH_1971	PTH_0922	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-5	MurI	PTH_2007	PTH_0787	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
AmiC-5	MurI-2	PTH_2007	PTH_0922	N-acetylmuramoyl-L-alanine amidase.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.754
HgdB-2	MurI	PTH_0788	PTH_0787	benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.635
HgdB-2	PTH_0792	PTH_0788	PTH_0792	benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit; BcrC/BadD/HgdB.	Xanthosine triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.620
MurD	MurI	PTH_1863	PTH_0787	UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.973
MurD	MurI-2	PTH_1863	PTH_0922	UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.971
MurD	PurL-2	PTH_1863	PTH_1430	UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.	Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with [...]	0.900
MurI	AmiC	PTH_0787	PTH_0361	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	N-acetylmuramoyl-L-alanine amidase.	0.754
MurI	AmiC-2	PTH_0787	PTH_0438	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	N-acetylmuramoyl-L-alanine amidase.	0.759
MurI	AmiC-3	PTH_0787	PTH_1425	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	N-acetylmuramoyl-L-alanine amidase.	0.754
MurI	AmiC-4	PTH_0787	PTH_1971	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	N-acetylmuramoyl-L-alanine amidase.	0.754

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