Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CaiD-2enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (263 aa)    
Predicted Functional Partners:
FadB
3-hydroxyacyl-CoA dehydrogenase.
 0.981
PaaJ
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.978
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 0.919
BaeS-4
Signal transduction histidine kinase.
   
 0.894
SodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.795
RpsB
Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
 0.790
RpsO
Ribosomal protein S15P/S13E; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
    
 
 0.774
RpsF
Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
    
 
 0.770
RpmG
Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
    
 
 0.769
RpsE
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
    
 
 0.766
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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