Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
PTH_0802Hypothetical reguration protein. (162 aa)    
Predicted Functional Partners:
PTH_0142
Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198).
  
 
 0.651
PTH_1153
Hypothetical membrane protein.
  
     0.593
GyrB
Type IIA topoisomerase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.545
DnaG-2
DNA primase; Bacterial type.
 
  
 0.532
PTH_1102
Hypothetical protein; Containing fibronectin type 3 domain.
 
 
 
 0.521
PTH_2197
Hypothetical protein.
 
    0.500
PTH_2193
Hypothetical protein; Containing partial COG5410, Uncharacterized protein conserved in bacteria and partial COG5362, Phage-related terminase.
 
     0.482
PTH_0799
Hypothetical signaling protein; Containing partial COG1418, predicted HD superfamily hydrolase.
   
   0.470
PTH_0800
Hypothetical protein.
       0.447
PTH_0801
Hypothetical protein; Containing FOG:CBS domain (COG0517) and GGDEF domain.
       0.447
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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