Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ComEC-2Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. (809 aa)    
Predicted Functional Partners:
Smf
Predicted Rossmann fold nucleotide-binding protein; Involved in DNA uptake.
 
  
 0.917
ComFC
Predicted amidophosphoribosyltransferases.
 
  
 0.893
PTH_0854
Hypothetical membrane protein; Containing DNA uptake protein and related DNA-binding protein region (ComEA, COG1555).
 
  
 0.876
PulO
Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.811
FimT
Tfp pilus assembly protein FimT.
 
  
 0.770
PTH_1156
Hypothetical protein; Containing PulG (COG2165), type II secretory pathway, pseudopilin PulG and COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor.
 
  
 0.754
HolA
DNA polymerase III, delta subunit.
 
   
 0.748
ComEB
Deoxycytidylate deaminase.
  
  
 0.726
PTH_0856
Hypothetical protein; Containing partial COG3953, SLT domain proteins.
       0.717
PTH_1690
Predicted ATPase; With chaperone activity.
 
  
 0.717
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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