HolA protein (Pelotomaculum thermopropionicum)

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[Homology]

Score

HolA

DNA polymerase III, delta subunit. (358 aa)

Predicted Functional Partners:

DnaN

0.994

DnaX

0.991

XerD

0.989

DnaE

0.989

PTH_0866

0.798

UraA

0.789

ComEC-2

0.748

PolA

0.656

dinG

0.655

RecO

0.613

Your Current Organism:

Pelotomaculum thermopropionicum

NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ComEC-2	HolA	PTH_0857	PTH_0867	Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region.	DNA polymerase III, delta subunit.	0.748
ComEC-2	RecO	PTH_0857	PTH_0897	Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region.	Recombinational DNA repair protein; Involved in DNA repair and RecF pathway recombination.	0.448
ComEC-2	dinG	PTH_0857	PTH_1414	Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region.	Hypothetical protein; 3'-5' exonuclease.	0.545
DnaE	DnaN	PTH_2220	PTH_0002	DNA polymerase III, alpha subunit.	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	0.989
DnaE	DnaX	PTH_2220	PTH_0063	DNA polymerase III, alpha subunit.	DNA polymerase III, gamma/tau subunits.	0.983
DnaE	HolA	PTH_2220	PTH_0867	DNA polymerase III, alpha subunit.	DNA polymerase III, delta subunit.	0.989
DnaE	PolA	PTH_2220	PTH_1976	DNA polymerase III, alpha subunit.	DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.745
DnaE	XerD	PTH_2220	PTH_0051	DNA polymerase III, alpha subunit.	DNA polymerase III, gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.982
DnaE	dinG	PTH_2220	PTH_1414	DNA polymerase III, alpha subunit.	Hypothetical protein; 3'-5' exonuclease.	0.657
DnaN	DnaE	PTH_0002	PTH_2220	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	DNA polymerase III, alpha subunit.	0.989
DnaN	DnaX	PTH_0002	PTH_0063	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	DNA polymerase III, gamma/tau subunits.	0.980
DnaN	HolA	PTH_0002	PTH_0867	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	DNA polymerase III, delta subunit.	0.994
DnaN	PolA	PTH_0002	PTH_1976	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.992
DnaN	RecO	PTH_0002	PTH_0897	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	Recombinational DNA repair protein; Involved in DNA repair and RecF pathway recombination.	0.412
DnaN	XerD	PTH_0002	PTH_0051	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	DNA polymerase III, gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.	0.987
DnaN	dinG	PTH_0002	PTH_1414	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	Hypothetical protein; 3'-5' exonuclease.	0.961
DnaX	DnaE	PTH_0063	PTH_2220	DNA polymerase III, gamma/tau subunits.	DNA polymerase III, alpha subunit.	0.983
DnaX	DnaN	PTH_0063	PTH_0002	DNA polymerase III, gamma/tau subunits.	DNA polymerase sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]	0.980
DnaX	HolA	PTH_0063	PTH_0867	DNA polymerase III, gamma/tau subunits.	DNA polymerase III, delta subunit.	0.991
DnaX	PolA	PTH_0063	PTH_1976	DNA polymerase III, gamma/tau subunits.	DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.	0.604

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