Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_0871Hypothetical membrane protein. (360 aa)    
Predicted Functional Partners:
PTH_0185
Hypothetical membrane protein.
  
   
 0.813
PTH_1605
Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
 
   
 0.813
RsbW
Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.808
gpr
peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
 
    0.803
PTH_2800
Hypothetical protein.
  
  
 0.802
PTH_1168
Hypothetical membrane protein.
  
  
 0.796
PTH_0124
Hypothetical protein.
  
   
 0.790
PTH_1173
Hypothetical protein.
  
   
 0.789
PTH_0889
Hypothetical membrane protein; Containing Yqf domain.
  
   
 0.787
PTH_1202
Predicted membrane-associated Zn-dependent protease 1.
  
   
 0.786
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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