STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_0902Uncharacterized protein conserved in bacteria; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (253 aa)    
Predicted Functional Partners:
PTH_0901
Predicted transcriptional regulator; Containing COG0517, FOG:CBS domain.
 
  
 0.964
PpsA
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
 
  
 0.951
LigT
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.679
GlyS
glycyl-tRNA synthetase, beta subunit.
  
    0.666
PTH_0801
Hypothetical protein; Containing FOG:CBS domain (COG0517) and GGDEF domain.
  
  
 0.642
Dgt
dGTP triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily.
       0.577
PpsA-2
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
  
  
 0.557
PTH_2377
Hypothetical protein; Containing COG3848, Phosphohistidine swiveling domain.
  
  
 0.557
GlyQ
glycyl-tRNA synthetase, alpha subunit.
       0.556
DnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.523
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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