Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
PTH_0926Uncharacterized conserved protein. (213 aa)    
Predicted Functional Partners:
ThiD
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase.
       0.778
ychF
Predicted GTPase, probable translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
  
    0.647
AraD
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases.
  
  
 0.640
PTH_0929
Hypothetical membrane protein.
 
     0.575
PflX
Uncharacterized Fe-S protein; Homolog of pyruvate formate lyase activating proteins.
 
     0.564
MET17
O-acetylhomoserine sulfhydrylase.
   
    0.560
GlyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
  0.500
PTH_0930
Hypothetical protein.
       0.479
PTH_0924
Hypothetical membrane protein.
       0.454
PTH_0182
Hypothetical protein.
  
     0.434
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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