Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TrxBThioredoxin reductase. (289 aa)    
Predicted Functional Partners:
TrxB-2
Thioredoxin reductase.
  
  
 
0.921
SelD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
     
 0.907
TrxA
Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 
 0.884
PTH_0650
Hypothetical protein.
  
 
 0.724
PTH_0963
Hypothetical protein.
       0.594
PTH_0937
Hypothetical membrane protein.
  
 
 0.581
guaB
Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.544
PTH_0961
Uncharacterized conserved protein.
       0.520
PTH_0267
Hypothetical protein; Containing NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family (COG1902) and TrxB, thioredoxin reductase (COG0492).
 
 
 0.467
NemA-2
NADH:flavin oxidoreductases; Containing TrxB (COG0492), thioredoxin reductase domain.
 
 
 0.465
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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