STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HemLGlutamate-1-semialdehyde aminotransferase. (434 aa)    
Predicted Functional Partners:
HemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.998
HemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.997
HemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.989
PTH_0973
uroporphyrinogen-III methylase and Uroporphyrinogen-III synthase; COG0007 CysG and COG1587 HemD.
 
  
 0.959
CysG
Siroheme synthase; Precorrin-2 oxidase/ferrochelatase domain.
   
 0.957
FabD
(acyl-carrier-protein) S-malonyltransferase.
    
 0.911
Lrp-2
Transcriptional regulator.
     
 0.829
Lrp
Transcriptional regulator.
     
 0.800
FabB
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
  
 0.778
PTH_0976
Predicted Fe-S oxidoreductases.
  
  
 0.759
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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