Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AspAAspartate ammonia-lyase. (472 aa)    
Predicted Functional Partners:
NadB
Aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
   
 0.917
PckA
Phosphoenolpyruvate carboxykinase; ATP; Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
 
 0.914
ArgH
Argininosuccinate lyase.
     
0.907
AsnB
Asparagine synthase; Glutamine-hydrolyzing.
     
 0.907
PTH_1421
Aspartate/tyrosine/aromatic aminotransferase.
     
 0.907
PTH_1798
Aspartate/tyrosine/aromatic aminotransferase.
     
 0.907
PurB
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
0.907
PurA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.907
PTH_1687
Asparaginase.
     
 0.902
PyrB
Aspartate carbamoyltransferase, catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.900
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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