| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BirA | ComEC-2 | PTH_0255 | PTH_0857 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.705 |
| BirA | PTH_0142 | PTH_0255 | PTH_0142 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | 0.498 |
| BirA | PTH_1236 | PTH_0255 | PTH_1236 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.848 |
| BirA | RssA | PTH_0255 | PTH_0989 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Predicted esterase; The alpha-beta hydrolase superfamily. | 0.408 |
| BirA | nadE | PTH_0255 | PTH_0918 | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.767 |
| ComEC-2 | BirA | PTH_0857 | PTH_0255 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.705 |
| ComEC-2 | PTH_0142 | PTH_0857 | PTH_0142 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | 0.693 |
| ComEC-2 | PTH_0988 | PTH_0857 | PTH_0988 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | ACT domain-containing protein; Belongs to the UPF0237 family. | 0.564 |
| ComEC-2 | PTH_1236 | PTH_0857 | PTH_1236 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.513 |
| ComEC-2 | RssA | PTH_0857 | PTH_0989 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Predicted esterase; The alpha-beta hydrolase superfamily. | 0.573 |
| ComEC-2 | nadE | PTH_0857 | PTH_0918 | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.401 |
| PTH_0142 | BirA | PTH_0142 | PTH_0255 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.498 |
| PTH_0142 | ComEC-2 | PTH_0142 | PTH_0857 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.693 |
| PTH_0142 | PTH_1236 | PTH_0142 | PTH_1236 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Hypothetical protein; Containing COG0517and COG0617 domains; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.670 |
| PTH_0142 | RssA | PTH_0142 | PTH_0989 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Predicted esterase; The alpha-beta hydrolase superfamily. | 0.545 |
| PTH_0142 | nadE | PTH_0142 | PTH_0918 | Hypothetical protein; Containing predicted ATPase (COG3899), FhlA, FOG: GAF domain (COG2203), S_TKc, serine/threonine protein kinases, catalytic domain, His Kinase A (phosphoacceptor), HATPase_c, Histidine kinase-like ATPase, REC, signal receiver domain, and ArcB, FOG: HPt domain (COG2198). | Hypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.608 |
| PTH_0987 | PTH_0988 | PTH_0987 | PTH_0988 | Uncharacterized conserved protein. | ACT domain-containing protein; Belongs to the UPF0237 family. | 0.961 |
| PTH_0987 | RssA | PTH_0987 | PTH_0989 | Uncharacterized conserved protein. | Predicted esterase; The alpha-beta hydrolase superfamily. | 0.489 |
| PTH_0988 | ComEC-2 | PTH_0988 | PTH_0857 | ACT domain-containing protein; Belongs to the UPF0237 family. | Predicted hydrolase; Metallo-beta-lactamase superfamily, containing predicted metal-binding region. | 0.564 |
| PTH_0988 | PTH_0987 | PTH_0988 | PTH_0987 | ACT domain-containing protein; Belongs to the UPF0237 family. | Uncharacterized conserved protein. | 0.961 |