STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CdhECO dehydrogenase/acetyl-CoA synthase gamma subunit; Corrinoid Fe-S protein. (445 aa)    
Predicted Functional Partners:
CdhD
CO dehydrogenase/acetyl-CoA synthase delta subunit; Corrinoid Fe-S protein.
 
 0.999
MetH
Methionine synthase I; Containing cobalamin-binding domain.
 
 0.999
PTH_1002
Uncharacterized metal-binding protein.
 
 
 0.996
CooC
CO dehydrogenase maturation factor.
 
  
 0.978
PTH_1005
Hypothetical protein.
 
   
 0.928
Acs-2
Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.928
MetF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
   
 0.917
HycB
Fe-S-cluster; Containing hydrogenase components 2.
     
 0.901
HycB-2
Fe-S-cluster-containing hydrogenase components 2.
     
 0.901
PTH_1873
Hypothetical protein.
  
   
 0.761
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.