Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PTH_1002Uncharacterized metal-binding protein. (631 aa)    
Predicted Functional Partners:
CdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit; Corrinoid Fe-S protein.
 
 
 0.996
CdhD
CO dehydrogenase/acetyl-CoA synthase delta subunit; Corrinoid Fe-S protein.
 
 
 
 0.990
MetH
Methionine synthase I; Containing cobalamin-binding domain.
 
 
 
 0.904
CooC
CO dehydrogenase maturation factor.
 
   
 0.902
PTH_1005
Hypothetical protein.
 
   
 0.875
MetF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
     0.821
PTH_1873
Hypothetical protein.
  
     0.554
PTH_0999
Hypothetical protein.
       0.550
PTH_2253
Predicted NADH:ubiquinone oxidoreductase.
  
     0.532
MIS1
Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
 
   
 0.510
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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