STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MetHMethionine synthase I; Containing cobalamin-binding domain. (264 aa)    
Predicted Functional Partners:
CdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit; Corrinoid Fe-S protein.
 
 0.999
CdhD
CO dehydrogenase/acetyl-CoA synthase delta subunit; Corrinoid Fe-S protein.
 
 
 0.999
MetF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
  
 0.980
PTH_1005
Hypothetical protein.
 
   
 0.917
PTH_1002
Uncharacterized metal-binding protein.
 
 
 
 0.913
CooC
CO dehydrogenase maturation factor.
 
   
 0.888
PTH_1873
Hypothetical protein.
 
  
 0.677
MIS1
Formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family.
 
   
 0.672
FolD
5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
     
 0.598
PTH_0952
precorrin-6B methylase 1,2; Containing COG2241 and COG2242.
  
   
 0.561
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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