Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1005Hypothetical protein. (223 aa)    
Predicted Functional Partners:
MetF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 0.993
CdhD
CO dehydrogenase/acetyl-CoA synthase delta subunit; Corrinoid Fe-S protein.
 
   
 0.936
CdhE
CO dehydrogenase/acetyl-CoA synthase gamma subunit; Corrinoid Fe-S protein.
 
   
 0.924
MetH
Methionine synthase I; Containing cobalamin-binding domain.
 
   
 0.903
CooC
CO dehydrogenase maturation factor.
 
   
 0.891
PTH_1002
Uncharacterized metal-binding protein.
 
   
 0.875
NapF
Ferredoxin.
   
 
 0.774
PTH_2253
Predicted NADH:ubiquinone oxidoreductase.
  
     0.750
PTH_1873
Hypothetical protein.
  
     0.692
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.647
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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