SdhC protein (Pelotomaculum thermopropionicum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

SdhC

Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (233 aa)

Predicted Functional Partners:

SdhA-2

0.999

SdhB

0.999

MmcD1

0.989

SdhA-3

0.975

SdhB-2

0.973

MmcD2

0.963

SdhA

0.952

MmcB

0.945

MmcC

0.938

NapF

0.825

Your Current Organism:

Pelotomaculum thermopropionicum

NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MmcB	MmcC	PTH_1356	PTH_1357	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	0.999
MmcB	MmcD1	PTH_1356	PTH_1358	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.557
MmcB	SdhA	PTH_1356	PTH_0239	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.504
MmcB	SdhA-2	PTH_1356	PTH_1017	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.948
MmcB	SdhA-3	PTH_1356	PTH_1491	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.504
MmcB	SdhB	PTH_1356	PTH_1018	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.947
MmcB	SdhB-2	PTH_1356	PTH_1490	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.500
MmcB	SdhC	PTH_1356	PTH_1016	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.945
MmcC	MmcB	PTH_1357	PTH_1356	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	0.999
MmcC	MmcD1	PTH_1357	PTH_1358	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.508
MmcC	MmcD2	PTH_1357	PTH_1359	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	succinyl-CoA synthetase, alpha subunit.	0.496
MmcC	SdhA	PTH_1357	PTH_0239	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.504
MmcC	SdhA-2	PTH_1357	PTH_1017	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.948
MmcC	SdhA-3	PTH_1357	PTH_1491	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.	0.504
MmcC	SdhB	PTH_1357	PTH_1018	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.949
MmcC	SdhB-2	PTH_1357	PTH_1490	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.	0.514
MmcC	SdhC	PTH_1357	PTH_1016	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.	0.938
MmcD1	MmcB	PTH_1358	PTH_1356	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Fumarase, N-terminal domain; Fumarate hydratase (COG1951), TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain.	0.557
MmcD1	MmcC	PTH_1358	PTH_1357	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Fumarase, C-terminal domain; Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.	0.508
MmcD1	MmcD2	PTH_1358	PTH_1359	succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	succinyl-CoA synthetase, alpha subunit.	0.999

page 1 of 5

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Co-occurrence

Textmining

Co-expression

© STRING Consortium 2026

Credits

Access

Info

About