| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AlaS | AlaS-2 | PTH_1060 | PTH_1061 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | alanyl-tRNA synthetase. | 0.999 |
| AlaS | PTH_1063 | PTH_1060 | PTH_1063 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | 0.400 |
| AlaS | PTH_1065 | PTH_1060 | PTH_1065 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.749 |
| AlaS-2 | AlaS | PTH_1061 | PTH_1060 | alanyl-tRNA synthetase. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.999 |
| AlaS-2 | PTH_1065 | PTH_1061 | PTH_1065 | alanyl-tRNA synthetase. | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.672 |
| ArgA | PTH_1063 | PTH_1062 | PTH_1063 | N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | 0.522 |
| ArgA | PTH_1065 | PTH_1062 | PTH_1065 | N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.494 |
| ArgA | PTH_1066 | PTH_1062 | PTH_1066 | N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. | Hypothetical protein; Belongs to the UPF0473 family. | 0.475 |
| ArgA | Tas | PTH_1062 | PTH_1064 | N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. | Predicted oxidoreductases; Related to aryl-alcohol dehydrogenases. | 0.506 |
| MiaA | PTH_1065 | PTH_1344 | PTH_1065 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.611 |
| MiaA | SpoU | PTH_1344 | PTH_0299 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.470 |
| PTH_1063 | AlaS | PTH_1063 | PTH_1060 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.400 |
| PTH_1063 | ArgA | PTH_1063 | PTH_1062 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | N-acetylglutamate synthase and related acetyltransferases; Belongs to the acetyltransferase family. | 0.522 |
| PTH_1063 | PTH_1065 | PTH_1063 | PTH_1065 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.958 |
| PTH_1063 | PTH_1066 | PTH_1063 | PTH_1066 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | Hypothetical protein; Belongs to the UPF0473 family. | 0.688 |
| PTH_1063 | PTH_1067 | PTH_1063 | PTH_1067 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | Uncharacterized vancomycin resistance protein. | 0.416 |
| PTH_1063 | Tas | PTH_1063 | PTH_1064 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | Predicted oxidoreductases; Related to aryl-alcohol dehydrogenases. | 0.793 |
| PTH_1063 | mltG | PTH_1063 | PTH_1068 | Uncharacterized protein conserved in bacteria; Belongs to the UPF0297 family. | Predicted periplasmic solute-binding protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.485 |
| PTH_1065 | AlaS | PTH_1065 | PTH_1060 | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.749 |
| PTH_1065 | AlaS-2 | PTH_1065 | PTH_1061 | Predicted endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | alanyl-tRNA synthetase. | 0.672 |