Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FliADNA-directed RNA polymerase specialized sigma subunit; Belongs to the sigma-70 factor family. (243 aa)    
Predicted Functional Partners:
PilO-2
Tfp pilus assembly protein PilO.
 
   
 0.856
FlgM
Negative regulator of flagellin synthesis; Anti-sigma28 factor.
  
 
 0.827
RpoB
DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.795
PilM-2
Tfp pilus assembly protein, ATPase PilM.
     
 0.786
PulF-2
Type II secretory pathway, component PulF.
       0.781
RpoA
DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.779
PolA-2
DNA polymerase I - 3'-5' exonuclease and polymerase domains.
 
 
 0.774
RpoC
DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.761
RsbW
Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.760
CheR
Methylase of chemotaxis methyl-accepting proteins.
  
  
 0.707
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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