| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CarA | GltD-2 | PTH_1810 | PTH_0735 | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.902 |
| CarA | GltD-3 | PTH_1810 | PTH_1181 | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.902 |
| CarA | PyrD | PTH_1810 | PTH_1806 | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.965 |
| CarA | PyrE | PTH_1810 | PTH_1804 | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.948 |
| CarA | UbiB | PTH_1810 | PTH_1180 | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.697 |
| FolD | GltD-3 | PTH_1183 | PTH_1181 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.633 |
| FolD | PyrE | PTH_1183 | PTH_1804 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.424 |
| FolD | UbiB | PTH_1183 | PTH_1180 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.712 |
| FolD | XseA | PTH_1183 | PTH_1182 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.985 |
| GltD | PTH_1502 | PTH_0444 | PTH_1502 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Hypothetical protein. | 0.761 |
| GltD | PTH_2646 | PTH_0444 | PTH_2646 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Hypothetical formate dehydrogenase; Containing partial COG3383, Uncharacterized anaerobic dehydrogenase. | 0.905 |
| GltD | PyrD | PTH_0444 | PTH_1806 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.483 |
| GltD | UbiB | PTH_0444 | PTH_1180 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.974 |
| GltD-2 | CarA | PTH_0735 | PTH_1810 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.902 |
| GltD-2 | GltD-3 | PTH_0735 | PTH_1181 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.912 |
| GltD-2 | PTH_2646 | PTH_0735 | PTH_2646 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Hypothetical formate dehydrogenase; Containing partial COG3383, Uncharacterized anaerobic dehydrogenase. | 0.893 |
| GltD-2 | UbiB | PTH_0735 | PTH_1180 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases. | 0.938 |
| GltD-3 | CarA | PTH_1181 | PTH_1810 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | Carbamoylphosphate synthase small subunit; Belongs to the CarA family. | 0.902 |
| GltD-3 | FolD | PTH_1181 | PTH_1183 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.633 |
| GltD-3 | GltD-2 | PTH_1181 | PTH_0735 | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.912 |