Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PycAPyruvate carboxylase. (72 aa)    
Predicted Functional Partners:
BirA
biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.913
AccC
Biotin carboxylase.
  
 0.810
PykF
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.739
MmcH
acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta).
  
 0.734
PTH_1188
Uncharacterized proteins, homologs of lactam utilization protein B; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
       0.691
PTH_1174
Hypothetical protein; Containing COG5016 and COG0511 domains.
  
  
 0.653
PTH_1187
Hypothetical protein.
     
 0.613
DUR1
Allophanate hydrolase subunit 1.
 
     0.592
PTH_1191
Hypothetical membrane protein.
       0.574
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
      
 0.547
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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