node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HemC | PolA | PTH_0972 | PTH_1976 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.406 |
HemC | XseB | PTH_0972 | PTH_1193 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.601 |
IspA-2 | RocR-3 | PTH_1194 | PTH_1192 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Transcriptional regulator; Containing PAS, AAA-type ATPase, and DNA-binding domains. | 0.521 |
IspA-2 | XseA | PTH_1194 | PTH_1182 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.805 |
IspA-2 | XseB | PTH_1194 | PTH_1193 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.933 |
IspA-2 | ispH | PTH_1194 | PTH_1619 | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.945 |
PTH_1120 | PolA | PTH_1120 | PTH_1976 | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.751 |
PTH_1120 | TopA | PTH_1120 | PTH_1246 | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.424 |
PTH_1120 | XseB | PTH_1120 | PTH_1193 | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.505 |
PTH_1120 | dinG | PTH_1120 | PTH_1414 | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | Hypothetical protein; 3'-5' exonuclease. | 0.495 |
PTH_1120 | ispH | PTH_1120 | PTH_1619 | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.511 |
PolA | HemC | PTH_1976 | PTH_0972 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.406 |
PolA | PTH_1120 | PTH_1976 | PTH_1120 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Hypothetical protein; Containing two Glycos_transf_2, Glycosyl transferase domain, TPR, Tetratricopeptide repeat domain and partial COG1216, predicted glycosyltransferases. | 0.751 |
PolA | TopA | PTH_1976 | PTH_1246 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.902 |
PolA | XseA | PTH_1976 | PTH_1182 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Exonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.689 |
PolA | XseB | PTH_1976 | PTH_1193 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Exonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.502 |
PolA | YajC | PTH_1976 | PTH_1033 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Preprotein translocase subunit YajC. | 0.589 |
PolA | dinG | PTH_1976 | PTH_1414 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Hypothetical protein; 3'-5' exonuclease. | 0.966 |
PolA | ispH | PTH_1976 | PTH_1619 | DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Hypothetical protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.678 |
RocR-3 | IspA-2 | PTH_1192 | PTH_1194 | Transcriptional regulator; Containing PAS, AAA-type ATPase, and DNA-binding domains. | Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.521 |