STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1202Predicted membrane-associated Zn-dependent protease 1. (430 aa)    
Predicted Functional Partners:
CitB
Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
   
 0.988
gpr
peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
    0.811
FliA-4
DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.807
PTH_0124
Hypothetical protein.
  
   
 0.806
PTH_0185
Hypothetical membrane protein.
  
   
 0.805
PTH_1605
Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.804
PTH_2800
Hypothetical protein.
  
   
 0.804
PTH_1169
Hypothetical membrane protein.
 
     0.802
PTH_0871
Hypothetical membrane protein.
  
   
 0.799
PTH_1168
Hypothetical membrane protein.
 
     0.797
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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