node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FliA-2 | GerA | PTH_1226 | PTH_1231 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Bacillus/Clostridium GerA spore germination protein. | 0.777 |
FliA-2 | PTH_1228 | PTH_1226 | PTH_1228 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical membrane protein. | 0.870 |
FliA-2 | PTH_1229 | PTH_1226 | PTH_1229 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein]. | 0.853 |
FliA-2 | PTH_1230 | PTH_1226 | PTH_1230 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical membrane protein. | 0.836 |
FliA-2 | PTH_1605 | PTH_1226 | PTH_1605 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.773 |
FliA-2 | PTH_1840 | PTH_1226 | PTH_1840 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Hypothetical membrane protein; Containing GerA domain (pfam03323). | 0.675 |
FliA-2 | PTH_1844 | PTH_1226 | PTH_1844 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Uncharacterized conserved protein. | 0.697 |
FliA-2 | RsbW | PTH_1226 | PTH_1225 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.976 |
FliA-2 | SpoIIAA | PTH_1226 | PTH_1224 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-anti-sigma regulatory factor; Antagonist of anti-sigma factor; Belongs to the anti-sigma-factor antagonist family. | 0.966 |
FliA-2 | gpr | PTH_1226 | PTH_1755 | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.738 |
GerA | FliA-2 | PTH_1231 | PTH_1226 | Bacillus/Clostridium GerA spore germination protein. | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.777 |
GerA | PTH_1228 | PTH_1231 | PTH_1228 | Bacillus/Clostridium GerA spore germination protein. | Hypothetical membrane protein. | 0.954 |
GerA | PTH_1229 | PTH_1231 | PTH_1229 | Bacillus/Clostridium GerA spore germination protein. | Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein]. | 0.962 |
GerA | PTH_1230 | PTH_1231 | PTH_1230 | Bacillus/Clostridium GerA spore germination protein. | Hypothetical membrane protein. | 0.966 |
GerA | PTH_1605 | PTH_1231 | PTH_1605 | Bacillus/Clostridium GerA spore germination protein. | Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.771 |
GerA | PTH_1844 | PTH_1231 | PTH_1844 | Bacillus/Clostridium GerA spore germination protein. | Uncharacterized conserved protein. | 0.693 |
GerA | RsbW | PTH_1231 | PTH_1225 | Bacillus/Clostridium GerA spore germination protein. | Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.793 |
GerA | SpoIIAA | PTH_1231 | PTH_1224 | Bacillus/Clostridium GerA spore germination protein. | Anti-anti-sigma regulatory factor; Antagonist of anti-sigma factor; Belongs to the anti-sigma-factor antagonist family. | 0.791 |
GerA | gpr | PTH_1231 | PTH_1755 | Bacillus/Clostridium GerA spore germination protein. | peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.780 |
PTH_1228 | FliA-2 | PTH_1228 | PTH_1226 | Hypothetical membrane protein. | DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.870 |