STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1230Hypothetical membrane protein. (118 aa)    
Predicted Functional Partners:
PTH_1229
Hypothetical protein; Containing partial FabH (COG0332), 3-oxoacyl-[acyl-carrier-protein].
 
  
 0.979
PTH_1228
Hypothetical membrane protein.
 
  
 0.969
GerA
Bacillus/Clostridium GerA spore germination protein.
 
   
 0.966
RsbW
Anti-sigma regulatory factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
     0.875
FliA-2
DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.836
SpoIIAA
Anti-anti-sigma regulatory factor; Antagonist of anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
 
     0.818
PTH_1840
Hypothetical membrane protein; Containing GerA domain (pfam03323).
  
  
 0.795
gpr
peptidase_U3, Germination protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
  
 0.788
FliA-4
DNA-directed RNA polymerase specialized sigma subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.788
AbrB-2
Regulators of stationary/sporulation gene expression.
  
    0.779
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.