Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTH_1284Hypothetical protein; Containing partial CysG (COG1648), siroheme synthase (precorrin-2 oxidase/ferrochelatase domain). (296 aa)    
Predicted Functional Partners:
Dfp
Phosphopantothenoylcysteine synthetase/decarboxylase.
 
  
 0.990
Asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
 0.689
DapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
       0.688
PTH_1978
Predicted membrane protein; Probably functions as a manganese efflux pump.
  
     0.649
PTH_1605
Hypothetical protein; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.628
AbrB-2
Regulators of stationary/sporulation gene expression.
  
   
 0.616
PTH_1230
Hypothetical membrane protein.
  
   
 0.582
GerA
Bacillus/Clostridium GerA spore germination protein.
  
   
 0.572
DapA
Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.564
PTH_1281
Uncharacterized conserved protein.
 
     0.563
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
Server load: low (10%) [HD]