node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FolD | MmcM | PTH_1183 | PTH_1369 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.711 |
FolD | PTH_1304 | PTH_1183 | PTH_1304 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Uncharacterized protein conserved in bacteria. | 0.720 |
FolD | cinA | PTH_1183 | PTH_1300 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Conjugated protein of two COG1058, predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family. | 0.524 |
FolD | rny | PTH_1183 | PTH_1302 | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.475 |
MmcM | FolD | PTH_1369 | PTH_1183 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.711 |
MmcM | PTH_1304 | PTH_1369 | PTH_1304 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | Uncharacterized protein conserved in bacteria. | 0.449 |
MmcM | PTH_1306 | PTH_1369 | PTH_1306 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.478 |
MmcM | RecA | PTH_1369 | PTH_1301 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | RecA/RadA recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.749 |
MmcM | SpoVS | PTH_1369 | PTH_1305 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | Uncharacterized protein conserved in bacteria. | 0.437 |
MmcM | rny | PTH_1369 | PTH_1302 | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | Hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.518 |
PTH_1303 | PTH_1304 | PTH_1303 | PTH_1304 | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | Uncharacterized protein conserved in bacteria. | 0.827 |
PTH_1303 | PTH_1306 | PTH_1303 | PTH_1306 | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.440 |
PTH_1303 | PTH_1307 | PTH_1303 | PTH_1307 | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | Predicted metal-dependent phosphoesterases; PHP family. | 0.405 |
PTH_1303 | SpoVS | PTH_1303 | PTH_1305 | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | Uncharacterized protein conserved in bacteria. | 0.545 |
PTH_1303 | rny | PTH_1303 | PTH_1302 | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | Hypothetical protein; Endoribonuclease that initiates mRNA decay. | 0.719 |
PTH_1304 | FolD | PTH_1304 | PTH_1183 | Uncharacterized protein conserved in bacteria. | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.720 |
PTH_1304 | MmcM | PTH_1304 | PTH_1369 | Uncharacterized protein conserved in bacteria. | Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.449 |
PTH_1304 | PTH_1303 | PTH_1304 | PTH_1303 | Uncharacterized protein conserved in bacteria. | Hypothetical protein; Containing COG1431, Uncharacterized protein containing piwi/argonaute domain. | 0.827 |
PTH_1304 | PTH_1306 | PTH_1304 | PTH_1306 | Uncharacterized protein conserved in bacteria. | Zn-dependent dipeptidase, microsomal dipeptidase homolog. | 0.535 |
PTH_1304 | PTH_1307 | PTH_1304 | PTH_1307 | Uncharacterized protein conserved in bacteria. | Predicted metal-dependent phosphoesterases; PHP family. | 0.509 |