STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MmcD2succinyl-CoA synthetase, alpha subunit. (162 aa)    
Predicted Functional Partners:
MmcD1
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
MmcD2-2
succinyl-CoA synthetase, alpha subunit.
     0.991
SdhB-2
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 0.981
MmcE
methylmalonyl-CoA mutase, N-terminal domain/subunit.
    
 0.978
SdhB
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
 0.977
MmcF
methylmalonyl-CoA mutase, C-terminal domain/subunit; Cobalamin-binding.
    
 0.976
SdhA-3
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 0.974
SdhA-2
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit.
 0.971
MmcM
Related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
  
 
 0.970
SdhC
Succinate dehydrogenase/fumarate reductase, cytochrome b subunit.
  
 
 0.967
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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