Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CaiC-2acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (443 aa)    
Predicted Functional Partners:
CaiC-4
acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
  
  
 
0.922
FabD
(acyl-carrier-protein) S-malonyltransferase.
 
  
 0.909
FabB
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.905
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.772
FabG-3
Dehydrogenases with different specificities; Related to short-chain alcohol dehydrogenases.
 
 
 0.680
HemL
Glutamate-1-semialdehyde aminotransferase.
 
  
 0.659
PaaK
Coenzyme F390 synthetase.
     
 0.621
PaaK-2
Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
     
 0.621
PaaK-3
Coenzyme F390 synthetase.
     
 0.621
PaaK-4
Coenzyme F390 synthetase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
     
 0.621
Your Current Organism:
Pelotomaculum thermopropionicum
NCBI taxonomy Id: 370438
Other names: P. thermopropionicum SI, Pelotomaculum thermopropionicum SI, Pelotomaculum thermopropionicum str. SI, Pelotomaculum thermopropionicum strain SI
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